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UPB Earnings Date: Nov 4, 2026 (Estimated) — Upstream Bio, Inc.

NASDAQ · Healthcare · Biotechnology

Updated

Price $3.30
Market Cap $180.7M
P/E -0.9
52W Range $2.68 – $33.68
Next Earnings · Before open (est.)

When is UPB's next earnings date?

Upstream Bio, Inc. (UPB) is expected to report Q3 2026 earnings on Wednesday, November 4, 2026 at 7:00 AM ET (before market open); the date is an estimate and has not been confirmed by the company. The consensus estimate is EPS of -$0.73 on revenue of $522,455.

How did UPB do in its last earnings report?

In its most recent report on Aug 11, 2026 (Q2 2026), Upstream Bio, Inc. posted EPS of -$0.73 versus the -$0.78 estimate, a beat of 4.0%. Revenue was $773,000 against a $431,143 estimate. The stock's 1-day post-earnings move was -4.7%.

How much does UPB stock move after earnings?

UPB beat EPS estimates in 3 of its last 6 reported quarters. Over the last 7 reports the stock moved an average of 4.9% (up or down) in the day after earnings.

About Upstream Bio, Inc.

Upstream Bio, Inc. is a biotechnology company in the clinical development stage, dedicated to innovating therapies for inflammatory conditions, particularly those affecting the severe respiratory system. Its pipeline notably features verekitug, a monoclonal antibody designed to selectively target and suppress the thymic stromal lymphopoietin receptor. Beyond this, the company is actively developing treatments for severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Established in 2021, Upstream Bio maintains its operational base in Waltham, Massachusetts.

Earnings History

DatePeriodEPS Est.EPS Act.SurpriseRevenueResult1D Δ1W Δ1M Δ
2026-08-11Q2 2026-0.78-0.73+3.95%$773,000✅ Beat-4.70%-4.03%-19.89%
2026-05-13Q1 2026-0.76-0.75+1.32%$1.0M✅ Beat+4.58%-10.28%-28.72%
2026-03-26Q4 2025-0.71-0.78-9.86%$668,000❌ Miss+3.38%-1.69%-1.80%
2025-11-05Q3 2025-0.78-0.63+19.23%$683,000✅ Beat-4.27%-5.03%+10.78%
2025-08-06Q2 2025-0.61-0.74-21.31%$937,000❌ Miss+7.87%+12.90%+26.97%
2025-03-12Q4 2024-0.48-0.48+0.00%$613,000➖ Inline+7.83%+5.61%-23.71%
2024-11-07Q3 2024—-6.96—$607,000—+1.69%-2.48%-10.27%

Showing last 7 quarters.

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Financial data from licensed market-data providers; risk factors from SEC EDGAR filings. AI-powered analysis. Data last updated .