SPRO Earnings Date: Nov 12, 2026 (Estimated) — Spero Therapeutics, Inc.
NASDAQ · Healthcare · Biotechnology
Updated
When is SPRO's next earnings date?
Spero Therapeutics, Inc. (SPRO) is expected to report Q3 2026 earnings on Thursday, November 12, 2026 at 4:00 PM ET (after market close); the date is an estimate and has not been confirmed by the company. The consensus estimate is EPS of -$0.47.
How did SPRO do in its last earnings report?
In its most recent report on Aug 12, 2026 (Q2 2026), Spero Therapeutics, Inc. posted EPS of -$0.16 versus the -$0.17 estimate, a beat of 5.9%. Revenue was $0. The stock's 1-day post-earnings move was +4.2%.
How much does SPRO stock move after earnings?
SPRO beat EPS estimates in 6 of its last 8 reported quarters. Over the last 8 reports the stock moved an average of 7.2% (up or down) in the day after earnings.
About Spero Therapeutics, Inc.
Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States. The company's pipeline includes several key therapeutic candidates: tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic designed to address complicated urinary tract infections (cUTIs), including pyelonephritis, in adult patients. SPR206, an intravenously administered agent specifically developed to combat MDR Gram-negative bacterial infections in hospital environments. SPR720, an oral antibiotic targeting non-tuberculous mycobacterial (NTM) pulmonary disease. Spero Therapeutics has also forged several strategic alliances: A licensing agreement with Meiji Seika Pharma Co., Ltd. supports the ongoing development of tebipenem HBr. A separate licensing deal with Everest Medicines grants rights for the development, manufacturing, and commercialization of SPR206 across Greater China, South Korea, and various Southeast Asian nations. The company collaborates with the Bill & Melinda Gates Medical Research Institute to advance SPR720 for treating lung infections caused by Mycobacterium tuberculosis. Furthermore, a licensing agreement with Vertex Pharmaceuticals Incorporated covers patents associated with SPR720 and its active metabolite, SPR719. Founded in 2013, Spero Therapeutics maintains its corporate headquarters in Cambridge, Massachusetts.
Earnings History
| Date | Period | EPS Est. | EPS Act. | Surprise | Revenue | Result | 1D Δ | 1W Δ | 1M Δ |
|---|---|---|---|---|---|---|---|---|---|
| 2026-08-12 | Q2 2026 | -0.17 | -0.16 | +5.88% | $0 | ✅ Beat | +4.20% | +3.36% | -5.04% |
| 2026-05-13 | Q1 2026 | -0.18 | -0.13 | +27.78% | $258,000 | ✅ Beat | +13.11% | +7.79% | +16.80% |
| 2026-03-26 | Q4 2025 | -0.25 | 0.53 | +312.00% | $41.3M | ✅ Beat | -1.69% | +2.53% | +12.66% |
| 2025-11-13 | Q3 2025 | -0.25 | -0.13 | +48.00% | $5.4M | ✅ Beat | -1.23% | -7.38% | -6.15% |
| 2025-08-12 | Q2 2025 | -0.34 | -0.03 | +91.18% | $14.2M | ✅ Beat | -18.01% | -22.03% | -17.37% |
| 2025-03-27 | Q4 2024 | -0.31 | -0.38 | -22.58% | $15.0M | ❌ Miss | -10.88% | -27.45% | -17.45% |
| 2024-11-14 | Q3 2024 | -0.36 | -0.32 | +11.11% | $13.5M | ✅ Beat | -5.60% | -4.80% | -14.40% |
| 2024-05-15 | Q1 2024 | -0.04 | -0.24 | -500.00% | $9.3M | ❌ Miss | -3.09% | -7.10% | -16.05% |
Showing last 8 quarters.