SEPN Earnings Date: Nov 9, 2026 (Estimated) — Septerna Inc
NASDAQ · Healthcare · Biotechnology
Updated
When is SEPN's next earnings date?
Septerna Inc (SEPN) is expected to report Q3 2026 earnings on Monday, November 9, 2026 at 7:00 AM ET (before market open); the date is an estimate and has not been confirmed by the company. The consensus estimate is EPS of -$0.41 on revenue of $20.8M.
How did SEPN do in its last earnings report?
In its most recent report on Aug 10, 2026 (Q2 2026), Septerna Inc posted EPS of -$0.29 versus the -$0.43 estimate, a beat of 40.8%. Revenue was $26.7M against a $19.2M estimate. The stock's 1-day post-earnings move was +22.9%.
How much does SEPN stock move after earnings?
SEPN beat EPS estimates in 5 of its last 7 reported quarters. Over the last 7 reports the stock moved an average of 6.6% (up or down) in the day after earnings.
About Septerna Inc
Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves’ disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women’s health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.
Earnings History
| Date | Period | EPS Est. | EPS Act. | Surprise | Revenue | Result | 1D Δ | 1W Δ | 1M Δ |
|---|---|---|---|---|---|---|---|---|---|
| 2026-08-10 | Q2 2026 | -0.43 | -0.29 | +40.82% | $26.7M | ✅ Beat | +22.93% | +13.77% | -2.27% |
| 2026-05-11 | Q1 2026 | -0.32 | -0.19 | +40.62% | $26.5M | ✅ Beat | +5.39% | +11.58% | +29.27% |
| 2026-03-09 | Q4 2025 | -0.22 | -0.24 | -9.09% | $24.1M | ❌ Miss | -3.58% | -13.49% | -15.73% |
| 2025-11-10 | Q3 2025 | -0.03 | 0.18 | +700.00% | $21.5M | ✅ Beat | -2.21% | +25.69% | +37.71% |
| 2025-08-11 | Q2 2025 | 0.54 | -0.56 | -203.70% | $119,000 | ❌ Miss | -2.52% | +0.87% | +28.11% |
| 2025-03-27 | Q4 2024 | -0.69 | -0.64 | +7.25% | $212,000 | ✅ Beat | +2.44% | -10.50% | +5.21% |
| 2024-11-20 | Q3 2024 | -10.69 | -8.40 | +21.42% | $176,000 | ✅ Beat | -7.02% | +0.33% | -3.31% |
Showing last 7 quarters.